Bat3 deficiency accelerates the degradation of Hsp70-2/HspA2 during spermatogenesis

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Bat3 deficiency accelerates the degradation of Hsp70-2/HspA2 during spermatogenesis

Meiosis is critical for sexual reproduction. During meiosis, the dynamics and integrity of homologous chromosomes are tightly regulated. The genetic and molecular mechanisms governing these processes in vivo, however, remain largely unknown. In this study, we demonstrate that Bat3/Scythe is essential for survival and maintenance of male germ cells (GCs). Targeted inactivation of Bat3/Scythe in ...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 2008

ISSN: 1540-8140,0021-9525

DOI: 10.1083/jcb.200802113